Author: Structural Heart Disease Australia

SHDA Research Update – February 2018

Welcome to the monthly SHDA Research Update. Our specialists have selected 3 seminal papers that have been recently published in each speciality (Cardiology, Cardiac Surgery, Cardiac Imaging, Perioperative Medicine).   Cardiology Summarised by Sarah Catchpoole Long C, et al. Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing. Sci Adv. 2018 Jan Duchenne muscular dystrophy (DMD) is an ultimately fatal degenerative muscular genetic disorder, with complications including dilated cardiomyopathy. CRISPR/Cas9 has been successfully applied to correct mutations to the dystrophin gene via a process the authors term myoediting. In contrast to previous genetic research in DMD,...

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